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The Optimality of the Genetic Code

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cyghost
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« Reply #45 on: September 22, 2009, 12:42:36 PM »

I didn't mean to imply the science is pointless. I'm sure research is ongoing and anything that adds to our knowledge is sweet.

For the purpose of our discussion here it merely seems that the implications are rather pointless, other than adding to what we know.

I was hoping for an understanding of why you made this very long post with all this heaps and heaps and heaps of information. Which I am finding some difficulty in discussing with you. I admit to some frustration with respects to that aspect.

Currently it seems weird, you made it to discuss it, but it doesn't feel like you are discussing. Am I wrong?
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Teleological
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« Reply #46 on: September 22, 2009, 14:19:49 PM »

I didn't mean to imply the science is pointless. I'm sure research is ongoing and anything that adds to our knowledge is sweet.

For the purpose of our discussion here it merely seems that the implications are rather pointless, other than adding to what we know.

I was hoping for an understanding of why you made this very long post with all this heaps and heaps and heaps of information. Which I am finding some difficulty in discussing with you. I admit to some frustration with respects to that aspect.

Currently it seems weird, you made it to discuss it, but it doesn't feel like you are discussing. Am I wrong?
You  are. The discussion seems to be stuck on 1 parameter.
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cyghost
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« Reply #47 on: September 22, 2009, 14:38:28 PM »

You  are. The discussion seems to be stuck on 1 parameter.
If that is true, I apologise. The reason may be that I found a website that easily explained in layman's terms.

 
I have been hoping you'd do the same with the rest of dem parameters (however many there may be, which is currently still a mystery) and / or give us some conclusion or summary to further discussion.
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Teleological
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« Reply #48 on: September 22, 2009, 14:49:51 PM »

Welcome to share the link so that all can read it.
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cyghost
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« Reply #49 on: September 22, 2009, 14:55:01 PM »

I did. Page one, reply 11. You supplied it.
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Teleological
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« Reply #50 on: May 04, 2010, 08:46:59 AM »

Another interesting article:
Extreme genetic code optimality from a molecular dynamics calculation of amino acid polar requirement.
Abstract:
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A molecular dynamics calculation of the amino acid polar requirement is used to score the canonical genetic code. Monte Carlo simulation shows that this computational polar requirement has been optimized by the canonical genetic code, an order of magnitude more than any previously known measure, effectively ruling out a vertical evolution dynamics. The sensitivity of the optimization to the precise metric used in code scoring is consistent with code evolution having proceeded through the communal dynamics of statistical proteins using horizontal gene transfer, as recently proposed. The extreme optimization of the genetic code therefore strongly supports the idea that the genetic code evolved from a communal state of life prior to the last universal common ancestor.

The conclusion:
Quote
In conclusion, earlier estimates of code optimality were understated by a statistically significant amount. The extent of optimality and its dependence on metric revealed here further support the notion that the genetic code must have evolved during an early communal state of life


Evolutionary pressure to optimize the genetic code seemed to have diminished soon after the emergence of the last universal common ancestor.
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« Reply #51 on: May 05, 2010, 23:02:28 PM »

Evolutionary pressure to optimize the genetic code seemed to have diminished soon after the emergence of the last universal common ancestor.
Cite the paragraph in the paper that says that 'cos it looks a whole helluva lot like your usual conclusion jumping and fabrication. You know, where you pull a sterile gonad from your ass and call it a gemstone.
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